What is Agnus Castus?

What is Agnus Castus?

Agnus castus, also known as Vitex agnus-castus, chaste tree, or chasteberry, is a shrub native to the Mediterranean and Central Asia whose fruit and seeds are used in herbal supplements, primarily for women's health and is the primary ingredient in Prime Harmony.

Uses and Benefits

The primary use of Agnus castus is to help relieve symptoms of premenstrual syndrome (PMS) and other conditions related to the menstrual cycle. It is considered possibly effective for: 

• Premenstrual Syndrome (PMS): It is well-studied for reducing PMS symptoms such as irritability, mood swings, headaches, bloating, and menstrual cramps.
• Cyclical Breast Pain (Mastalgia): It seems to relieve breast pain and tenderness associated with the menstrual cycle.
• Menstrual Irregularities: It can help normalize menstruation cycles.
• Menopause Symptoms: The herb has been traditionally used to help manage symptoms during the peri-menopausal phase.
• Female Infertility: It is sometimes used for female infertility, particularly in cases linked to hormonal imbalances like low progesterone. 

Mechanism of Action

Agnus castus works by affecting the pituitary gland, the body's hormone control center. Its active compounds (diterpenes) bind to dopamine D2 receptors and help suppress the release of prolactin, a hormone that can contribute to PMS symptoms like sore breasts and mood swings. By lowering prolactin levels, it can help balance other hormones like estrogen and progesterone. 

Side Effects and Safety

Agnus castus is generally considered safe and well-tolerated, with side effects typically mild and reversible. Reported side effects may include nausea, headache, gastrointestinal disturbances, and skin rash. 

Important Considerations:

• Pregnancy and Breastfeeding: Use should be avoided during pregnancy and lactation due to its potential effects on hormone levels.
• Hormonal Medications: It might interfere with hormone-containing medications, including oral contraceptives (birth control pills) or hormone replacement therapy.
• Other Conditions: People with hormone-sensitive conditions, or those taking dopamine-related medications (such as some antipsychotics), should consult a healthcare provider before use. 

It often takes time to reach its full effect, with benefits typically noticed within one or two menstrual cycles, and potentially up to three months for maximum results.

You can read more about Agnus Castus here.

Agnus Castus is the main ingredient in Prime Harmony.